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Modeling Stroke in Mice: Transient Middle Cerebral Artery Occlusion via the External Carotid Artery

DOI :

10.3791/62573-v

May 24th, 2021

May 24th, 2021

5,548 Views

1Institute for Stroke and Dementia Research, LMU Munich, 2Munich Cluster for Systems Neurology (SyNergy)

Different models of middle cerebral artery occlusion (MCAo) are used in experimental stroke research. Here, an experimental stroke model of transient MCAo via the external carotid artery (ECA) is described, which aims to mimic human stroke, in which the cerebrovascular thrombus is removed due to spontaneous clot lysis or therapy.

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