Defining Gene Functions in Tumorigenesis by Ex vivo Ablation of Floxed Alleles in Malignant Peripheral Nerve Sheath Tumor Cells

0:52

Tumor Dissection and Staining

1:46

Ex Vivo Ablation of Floxed Erbb4 Alleles in MPNST Cells

3:52

Proliferation Assays in MPNST Cells with Ablated Erbb4 Alleles

4:23

RNA-Seq Analyses and Gene Identification with Altered Expression by Erbb4 Loss

6:04

Orthotopic Allograft of MPNST Cells with Ablated Erbb4 Alleles and Erbb4 Ablation Effects Analysis

7:10

Results: Effect of Adenovirus Transduction on MPNST Cells and Allografts

9:09

Conclusion