JoVE Logo
Faculty Resource Center

Sign In

Drug Treatment by Central Venous Catheter in a Mouse Model of Angiotensin II Induced Abdominal Aortic Aneurysm and Monitoring by 3D Ultrasound

DOI :

10.3791/64124-v

10:09 min

August 4th, 2022

August 4th, 2022

2,298 Views

1Division of Vascular Surgery, Department of General Surgery, Medical University of Vienna and Vienna General Hospital, 2Leeds Institute for Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, 3Leeds Vascular Institute, Leeds General Infirmary, 4Department for Visceral, Thoracic and Vascular Surgery, Technical University of Dresden and University Hospital Carl-Gustav Carus, 5Division of Cardiovascular and Interventional Radiology, Division of Molecular and Gender Imaging, Department of Biomedical Imaging and Image Guided Therapy, Medical University of Vienna and Vienna General Hospital

This protocol describes the consecutive implantation of an osmotic pump to induce abdominal aortic aneurysm by angiotensin II release in apolipoprotein E (ApoE) deficient mice and of a vascular access port with a jugular vein catheter for repeated drug treatment. Monitoring of aneurysm development by 3D ultrasound is effectively conducted despite dorsal implants.

Tags

Drug Treatment

-- Views

Related Videos

article

Hickman Catheter Use for Long-Term Vascular Access in a Preclinical Swine Model

article

A 3D Digital Model for the Diagnosis and Treatment of Pulmonary Nodules

article

Establishment and Confirmation of a Postnatal Right Ventricular Volume Overload Mouse Model

article

A Stable Phantom Material for Optical and Acoustic Imaging

article

Author Spotlight: Context Dependent Blood Collection Methods in Rats

article

Author Spotlight: Unveiling Prognostic Indicators in Heart Failure - The Role of Phase Angle and Bioelectrical Impedance Analysis

article

A Neonatal Heterotopic Rat Heart Transplantation Model for the Study of Endothelial-to-Mesenchymal Transition

article

Author Spotlight: Investigating the Effectiveness of Tuina Therapy for Frozen Shoulder

article

Author Spotlight: Enhancing Understanding and Treatment Strategies with the NEC-on-a-Chip Model

article

Author Spotlight: Alleviating Nausea and Vomiting in Pregnancy with Safe and Effective Auricular Acupuncture

JoVE Logo

Privacy

Terms of Use

Policies

Research

Education

ABOUT JoVE

Copyright © 2024 MyJoVE Corporation. All rights reserved