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Delivery of Cardioactive Therapeutics in a Porcine Myocardial Infarction Model

DOI :

10.3791/64177-v

7:20 min

February 10th, 2023

February 10th, 2023

647 Views

1Centre for Heart Research, The Westmead Institute for Medical Research, The University of Sydney, 2Department of Cardiology, Westmead Hospital, 3Sydney Imaging, Core Research Facility, The University of Sydney, 4Department of Cardiothoracic Surgery, Liverpool Hospital

The present protocol describes three methods of administering cardioactive therapeutic agents in a porcine model. Female landrace swine received treatment through either: (1) thoracotomy and transepicardial injection, (2) catheter-based transendocardial injection, or (3) intravenous infusion via jugular vein osmotic minipump.

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Cardioactive Therapeutics

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