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Improvement of a Closed Chest Porcine Myocardial Infarction Model by Standardization of Tissue and Blood Sampling Procedures

DOI :

10.3791/56856-v

March 12th, 2018

March 12th, 2018

10,625 Views

1Department for Biomedical Research, University of Bern, 2Graduate School for Cellular and Biomedical Sciences, University of Bern, 3Institute of Chemical Sciences and Engineering, Ecole Polytechnique Fédérale de Lausanne (EPFL)

Here we demonstrate a protocol to standardize sampling procedures of an established porcine model of acute myocardial infarction in order to increase its translational value in the understanding of the pathophysiology of myocardial ischemia/reperfusion injury and to test novel drug candidates.

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Keywords Porcine

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