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Establishing a Silicosis Rat Model via Exposure of Whole-Body to Respirable Silica

DOI :

10.3791/64467-v

October 28th, 2022

October 28th, 2022

957 Views

1Hebei Key Laboratory for Organ Fibrosis Research, School of Public Health, North China University of Science and Technology

This study describes a technique to establish a silicosis rat model with the inhalation of silica through the whole body in an inhalation chamber. The rats with silicosis could closely mimic the pathological process of human silicosis in an easy, cost-effective manner with good repeatability.

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