A Piglet Perinatal Asphyxia Model to Study Cardiac Injury and Hemodynamics after Cardiac Arrest, Resuscitation, and the Return of Spontaneous Circulation

1.7K Views

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10:55 min

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January 13th, 2023

DOI :

10.3791/64788-v

January 13th, 2023

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Eydis Oddsdottir Stenersen¹^,², Annette Olsen², Maria Melheim³, Rønnaug Solberg³^,⁴, Ingrid Dannevig⁵, Georg Schmölzer⁶^,⁷, Po-Yin Cheung⁶^,⁷, Britt Nakstad⁸^,⁹, Ola Didrik Saugstad¹⁰^,¹¹, Arild Rønnestad¹^,², Anne Lee Solevåg²

¹Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, ²Department of Neonatal Intensive Care, Division of Pediatric and Adolescent Medicine, Oslo University Hospital Rikshospitalet, ³Department of Pediatric Research, Division of Paediatric and Adolescent Medicine, Oslo University Hospital Rikshospitalet, ⁴Department of Pediatrics, Vestfold Hospital Trust, ⁵Department of Anesthesiology, Oslo University Hospital Rikshospitalet, ⁶Department of Pediatrics, Faculty of Medicine and Dentistry, University of Alberta, ⁷Centre for the Studies of Asphyxia and Resuscitation, Neonatal Research Unit, Royal Alexandra Hospital, ⁸Division of Paediatric and Adolescent Medicine, Institute of Clinical Medicine, University of Oslo, ⁹Department of Paediatrics and Adolescent Health, University of Botswana, ¹⁰Department of Pediatric Research, Oslo University Hospital, University of Oslo, ¹¹Department of Pediatrics, Robert H Lurie Medical Research Center, Northwestern University Chicago

Summary

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Piglet Perinatal Asphyxia

Cardiac Injury

Hemodynamics

Cardiac Arrest

Neonatal Resuscitation

Pathophysiology

Pulseless Electrical Activity

Surgical Intervention

Central Venous Catheter

Research Protocol

University Of Oslo

Chlorhexidine Sterilization

Internal Jugular Vein

Absorbable Sutures

Chapters in this video

0:04

Introduction

1:17

Surgical Intervention

4:53

Induction of Asphyxia and Cardiac Arrest

7:07

Cardiopulmonary Resuscitation (CPR)

9:04

Results: Monitoring the Hemodynamic and Physiological Changes During Asphyxia

10:15

Conclusion

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