In this study, gold standard polysomnography was used to assess sleep quality and the validated cognitive screening tool was used to evaluate cognitive function in major depressive disorder patients. Thinking to recently developed Chinese version of the cognitive screening tools has been confirmed to be a good tool for evaluation cognitive defects in Chinese patients with major depressive disorder. The current study reveals the close relationship between cognitive symptoms and sleep disorders in major depressive disorder patients.
To begin, collect the participant's demographics and instruct them to complete the Epworth Sleeping Scale. Lead the participant to the sleep monitoring room. Next, connect 15 electrodes of the electroencephalogram according to the International 10-20 system of electrode placement.
Also, connect the two derivations of electrooculogram near the participant's eyes. Three derivations of chin electromyogram, and two derivations of electrocardiogram. To acquire data, start the software by double clicking on device manager.
Double click the room option, add the personal information of the participant and click okay. Click start recording, followed by the calibration button. Instruct the participant to perform according to the step-by-step calibration procedure.
Keep the derivations in the correct position and collect the data for the entire night. On the next day, wake the participant by turning on the light of the sleep monitoring room. For post calibration, click the calibration button and instruct the participant to repeat the step-by-step calibration procedure, then click the close button to stop recording.
After recording, remove all the derivations, avoiding skin damage. Next, start the scoring system by double clicking the ProFusion PSG four button. Select the participant and click the scoring button.
Select the scoring automatically option to score sleep phases and arousals. Click the create button and lay out the results. Review the variables like time in bed, total sleep time, sleep latency, wake after sleep onset, sleep efficiency, and REM latency according to the PSG data and waves.
To begin, explain the procedure to the participants. Then double click the think it button to start the software. Enter the name, age, gender, dominant hand, educational level and location, and click the begin test button.
To evaluate subjective cognitive deficits, guide the patient to complete the perception deficits questionnaire. Read aloud, during the past seven days, how often did you have trouble getting things organized? And instruct the participant to choose one of the five response options.
Read the next question, during the past seven days, how often did you have trouble concentrating on what you were reading? And instruct the participant to choose one of the five response options. Again, read the question, during the past seven days, how often did you forget the date unless you looked it up?
And allow the participant to choose their response. Read the question, during the past seven days, how often did you forget what you talked about after a telephone conversation? And let the participant choose their response.
Finally, read aloud, during the past seven days, how often did you feel like your mind went totally blank? And instruct the participant to choose one of the five response options. Click the okay button to finish the assessment.
Using this protocol, 20 participants were evaluated for cognitive function using cognitive screening scores such as PDQ-5, SPO, SC, CB, and TMT-B.
