Manikandan Paramasivam

Laboratory of Molecular Gerontology, National Institute on Aging, National Institutes of Health

Affiliated withNational Institute on Aging, National Institutes of Health University of Copenhagen

Research Area

GeneticsBiology

Biography

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JoVE Journal Publications

Article Total : 2	Year
Publication title	2017
Publication title	2021

Other Publications

Article	Year
Purine twisted-intercalating nucleic acids: a new class of anti-gene molecules resistant to potassium-induced aggregation. Nucleic acids research\| PubMed ID: 18456705	2008
Structural polymorphism within a regulatory element of the human KRAS promoter: formation of G4-DNA recognized by nuclear proteins. Nucleic acids research\| PubMed ID: 18490377	2008
Triplex glue by synthesizing conjugated flexible intercalators. Nucleic acids symposium series (2004)\| PubMed ID: 18776241	2008
Protein hnRNPA1 binds to a critical G-rich element of KRAS and unwinds G-quadruplex structures: implications in transcription. Nucleic acids symposium series (2004)\| PubMed ID: 18776302	2008
Identification of a new G-quadruplex motif in the KRAS promoter and design of pyrene-modified G4-decoys with antiproliferative activity in pancreatic cancer cells. Journal of medicinal chemistry\| PubMed ID: 19099510	2009
Protein hnRNP A1 and its derivative Up1 unfold quadruplex DNA in the human KRAS promoter: implications for transcription. Nucleic acids research\| PubMed ID: 19282454	2009
Cellular uptake and binding of guanidine-modified phthalocyanines to KRAS/HRAS G-quadruplexes. Chemical communications (Cambridge, England)\| PubMed ID: 20062883	2010
The KRAS promoter responds to Myc-associated zinc finger and poly(ADP-ribose) polymerase 1 proteins, which recognize a critical quadruplex-forming GA-element. The Journal of biological chemistry\| PubMed ID: 20457603	2010
Primer extension reactions as a tool to uncover folding motifs within complex G-rich sequences: analysis of the human KRAS NHE. Chemical communications (Cambridge, England)\| PubMed ID: 21424008	2011
A ubiquitin-binding protein, FAAP20, links RNF8-mediated ubiquitination to the Fanconi anemia DNA repair network. Molecular cell\| PubMed ID: 22705371	2012
NEIL1 responds and binds to psoralen-induced DNA interstrand crosslinks. The Journal of biological chemistry\| PubMed ID: 23508956	2013
ATR-dependent phosphorylation of FANCM at serine 1045 is essential for FANCM functions. Cancer research\| PubMed ID: 23698467	2013
Arsenite binds to the RING finger domains of RNF20-RNF40 histone E3 ubiquitin ligase and inhibits DNA double-strand break repair. Journal of the American Chemical Society\| PubMed ID: 25170678	2014
Nuclear GIT2 is an ATM substrate and promotes DNA repair. Molecular and cellular biology\| PubMed ID: 25605334	2015
UHRF1 contributes to DNA damage repair as a lesion recognition factor and nuclease scaffold. Cell reports\| PubMed ID: 25818288	2015
MERIT40 cooperates with BRCA2 to resolve DNA interstrand cross-links. Genes & development\| PubMed ID: 26338419	2015
Single Molecule Analysis of Laser Localized Interstrand Crosslinks. Frontiers in genetics\| PubMed ID: 27242893	2016
Reconstitution of anaphase DNA bridge recognition and disjunction. Nature structural & molecular biology\| PubMed ID: 30177760	2018
PICH and TOP3A cooperate to induce positive DNA supercoiling. Nature structural & molecular biology\| PubMed ID: 30936532	2019