正确折叠和组装的蛋白质被选择性地包装成离开 ER 的囊泡。运动蛋白将这些囊泡运输到高尔基体,以添加修饰,使这些蛋白质在其目的地发挥作用。
高尔基体是一种真核细胞器,具有独特的带状外观。它是从急诊室到达的货物的主要分拣和调度站。新到达的囊泡进入最靠近急诊室的高尔基体顺式面,并通过一堆膜封闭的蓄水池运输。每个蓄水池都包含独特的酶组成,并执行特定的蛋白质修饰,例如磷酸化和糖基化。在跨脑池中修饰后,蛋白质被赋予定义其细胞目的地的标签。
根据分子标签,蛋白质被包装成囊泡并运输到特定的细胞位置,例如质膜。这些囊泡膜上的特异性标志物使它们能够停靠在适当的细胞位置。
来自章节 5:
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