Histochemical A-Beta Labeling of Cryostat Tissue Sections
5:00
Histochemical Labeling of Paraffin-Embedded Tissue Sections
5:42
A-Beta-Specific Antibody Labeling
7:24
Intracellular Amyloid-Beta Protein Colocalization
8:00
Results: Representative Curcumin-Amyloid Plaque Labeling and Imaging
9:24
Conclusion
副本
This protocol is the most efficient and cost-effective method for accurately labeling beta-amyloid plaques, as compared to amyloid-specific antibodies, which are currently the gold standard for labeling these plaques. This technique takes less tim
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Curcumin is an ideal fluorophore for labeling and imaging of amyloid beta protein plaques in brain tissue due to its preferential binding to amyloid beta protein as well as its structural similarities with other traditional amyloid binding dyes. It can be used to label and image amyloid beta protein plaques more efficiently and inexpensively than traditional methods.