Results: Study of the Spontaneous Recurring Seizures (SRS) After Electrical Kindling of VGAT-Cre Mice
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Conclusion
副本
This protocol generates a new model for temporal lobe epilepsy in which mice developed spontaneous seizures, and it's been very useful for probing the mechanisms of epileptogenesis and also for screening novel therapies. This procedure in VGAT-Cre
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This report describes the methods to generate a model of temporal lobe epilepsy based on the electrical kindling of transgenic VGAT-Cre mice. Kindled VGAT-Cre mice may be useful in determining what causes epilepsy and for screening novel therapies.