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Atmospheric-pressure Molecular Imaging of Biological Tissues and Biofilms by LAESI Mass Spectrometry

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09:22 min

September 3rd, 2010

September 3rd, 2010

14,005 Views

0:00

Title

0:41

Introduction

1:06

Tissue Preparation and Mounting

2:07

Optimization of the LAESI Ion Source

5:54

Molecular Imaging and Data Analysis

7:49

Mass Spectrometry of Biological Tissues Representative Results

8:44

Conclusion

Laser ablation electrospray ionization (LAESI) is an atmospheric-pressure ion source for mass spectrometry. In the imaging mode, a mid-infrared laser probes the distributions of molecules across a tissue section or a biofilm. This technique presents a new approach for diverse bioanalytical studies carried out under native experimental conditions.

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