Unopened Whole Aorta Oil Red O Staining and Imaging
4:43
En Face Aorta Mounting
5:39
Results: Representative Atherosclerotic Lesion Visualization and Quantification
6:57
Conclusion
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The quantification of atherosclerotic lesions in apoE and other types of hyperlipidemic mice is key to assessment of various genetic factors and new therapies. Our protocol provides step-by-step instructions for analysis of atherosclerotic burden
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This protocol provides a step-by-step procedure to analyze atherosclerotic burden in mice. Investigators can use this protocol to compare the abundance, location, and size of atherosclerotic lesions in different animals.