Culturing Commercialized pHGG Cell Line: UW479 and BT35
2:56
Co-Culture Protocol
3:59
Electrophysiological Recording
4:41
Results: Co-culture of Glutamatergic Neurons
6:55
Conclusion
Transcripción
The interactions between the malignant glioma cells and their surrounding neurons are gaining interest. Here, we show the development of an in vitro model co-culturing derived cortical glutamatergic neurons and tumor cells. The microfludic devices
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Recent works uncover the neuronal impact on high-grade pediatric glioma (pHGG) cells and their reciprocal interactions. The present work shows the development of an in vitro model co-culturing pHGG cells and glutamatergic neurons and recorded their electrophysiological interactions to mimic those interactivities.