April 21st, 2010
•Transverse aortic constriction (TAC) in the mouse is a commonly used experimental model to study mechanisms underlying cardiac hypertrophy and heart failure development. Here, we describe procedures to constrict the aorta to create a reproducible degree of cardiac hypertrophy in mice.
Vidéos Connexes
Heterotopic Heart Transplantation in Mice Video (Video) | JoVE
Creation of Murine Experimental Abdominal Aortic Aneurysms with Elastase Video (Video) | JoVE
Aortic Ring Assay Video (Video) | JoVE
Isolation and Primary Culture of Mouse Aortic Endothelial Cells Video (Video) | JoVE
Differentiation Capacity of Human Aortic Perivascular Adipose Progenitor Cells Video (Video) | JoVE
Induction of Right Ventricular Failure by Pulmonary Artery Constriction and Evaluation of Right Ventricular Function in Mice Video (Video) | JoVE
Isolation and Culture of Primary Aortic Endothelial Cells from Miniature Pigs Video (Video) | JoVE
Transverse Fracture of the Mouse Femur with Stabilizing Pin Video (Video) | JoVE
Isolation of Primary Patient-specific Aortic Smooth Muscle Cells and Semiquantitative Real-time Contraction Measurements In Vitro (Video) | JoVE
A Modified Technique for Transverse Aortic Constriction in Mice Video (Video) | JoVE