Results: Representative Cardiac Magnetic Resonance Imaging (MRI) and Wall Thickening Measurement
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Conclusion
Transcription
The overall goals of this surgical procedure are to create a clinically relevant model of chronic cardiac ischemia and to observe the effects of revascularization in this model using the current clinical therapy of coronary artery bypass graft sur
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This protocol presents a surgical large animal model of chronic, single vessel ischemia that results in regional abnormalities but does not create infarct, known as hibernating myocardium. Following establishment of chronic ischemia, animals are treated with off-pump LIMA-LAD coronary artery bypass graft surgery to revascularize the ischemic tissue.