Results: Optimizing Mitochondrial Modulator Concentrations and Cell Numbers for Monitoring Mitochondrial Respiration in Human Primary T Cells
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Conclusion
Transcription
Mitochondrial metabolism is an essential regulator of T cell durability and memory. Measuring mitochondrial respiration therefore gives important insights into the properties of T cells. The Seahorse machine can measure various elements of mitocho
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Metabolic adaptation is fundamental for T cells as it dictates differentiation, persistence, and cytotoxicity. Here, an optimized protocol for monitoring mitochondrial respiration in ex vivo cytokine-differentiated human primary T cells is presented.