Results: Analysis of MDA‐MB‐231 and AU565 MCTS Models
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Conclusion
Transcription
This protocol provides information on tumor model progression in a non-destructive manner. It also gives indications of therapeutic response through entire drug regimens within singular aggregates rather than relying on age match samples. Conventi
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The present protocol develops an image-based technique for rapid, non-destructive, and label-free regional cell density and viability measurement within 3D tumor aggregates. Findings revealed a cell-density gradient, with higher cell densities in core regions than outer layers in developing aggregates and predominantly peripheral cell death in HER2+ aggregates treated with Trastuzumab.