루게릭 병에 TDP-43 변종 형태론 특정 시약의 분리에 대한 소설 원자 힘 현미경 기반 Biopanning

Using atomic force microscopy in combination with biopanning technology we created a negative and positive biopanning system to acquire antibodies against disease-specific protein variants present in any biological material, even at low concentrations. We were successful in obtaining antibodies to TDP-43 protein variants involved in Amyotrophic Lateral Sclerosis.