The overall goal of this assay is to assess the anticoagulant properties of endothelial cells, using whole non-anticoagulated blood. This method can be used to answer research questions which are related to cardiovascular research, transportation
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We present an in vitro model which allows the study and analysis of coagulation in whole, non-anticoagulated blood. Anticoagulation in the system depends on the natural anticoagulation effect of healthy endothelial cells and endothelial cell activation will result in clotting.