Necrotic Cell Death-induced by Hyperactive Ion Channels
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Protein Aggregate-induced Neurodegeneration
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Representative Results: Monitor Necrotic Cell Death-Induced by Hyperactive Ion Channels and Protein Aggregate-induced Neurodegeneration
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Conclusion
필기록
Over the past decades, human lifespan is extended, due to improvements in standards of living and advances in medical science. Age is the biggest risk factor for many life-threatening diseases, including neurodegenerative disorders, such as Alzhei
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Here, we introduce and describe widely accessible methodologies utilizing some versatile nematode models, including hyperactivated ion channel-induced necrosis and protein aggregate-induced neurotoxicity, to monitor and dissect the cellular and molecular underpinnings of age-associated neurodegenerative diseases.