Cancer Resection Surgery: Distal Pancreatectomy and Splenectomy
4:56
Results: Observed Parameters during Assessment of Resection Mouse Model for Pancreatic Cancer
6:27
Conclusion
필기록
This protocol describes a robust and reproducible surgical resection model of pancreatic cancer in mice, which may be used for testing adjuvant and neoadjuvant therapy. This technique combines a co-infection orthotopic model, which is effective at
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In the clinical context, patients with localized pancreatic cancer will undergo pancreatectomy followed by adjuvant treatment. This protocol reported here aims to establish a safe and effective method of modelling this clinical scenario in nude mice, through orthotopic implantation of pancreatic cancer followed by distal pancreatectomy and splenectomy.