Induction of Noise‐Induced Hearing Loss (NIHL) in Mice
3:07
Auditory Brainstem Response (ABR)‐Based Assessment of Hearing Threshold
4:19
Microscope Examination
5:18
Results: Assessing Hearing Function and Outer Hair Cell Damage in NIHL Mice
6:32
Conclusion
필기록
Although there have been studies on noise-induced hearing loss, none have recorded the method in such detail, making this an important procedure. This method effectively caused noise-induced hearing loss in mice, and observes the actual changes in
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Here, we present a protocol for a mouse model of noise-induced hearing loss (NIHL). To induce NIHL, we developed a new and simple device using corrugated plastic, a rat trap cage, and a speaker. Auditory brainstem response and immunofluorescence imaging were employed to assess the hearing function and outer hair cell damage, respectively.