The protocol follows the guidelines of the Ethics Committee of the Third Hospital of Hebei Medical University. Informed consent was obtained from the patients for including them and the data generated as a part of this study.
1. Pre-operative preparation
<ol>
	<li>Select patients according to the following inclusion and exclusion criteria. For the patients undergoing the surgeries, the inclusion criteria are as follows: 1) nerve compression due to thoracolumbar kyphosis, 2) ...

<ol>
	<li>Petitt, J. C., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Failure+of+conservatively+managed+traumatic+vertebral+compression+fractures:+A+systematic+review.">Failure of conservatively managed traumatic vertebral compression fractures: A systematic review.</a> World Neurosurgery. 165, 81-88 (2022).</li><li>Li, Y., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Influence+of+lumbar+sagittal+profile+on+pelvic+orientation+and+pelvic+motion+during+postural+changes+in+patients+with+ankylosing+spondylitis-related+thoracolumbar+kyphosis+following+pedicle+subtraction+osteotomy.">Influence of lumbar sagittal profile on pelvic orientation and pelvic motion during postural changes in patients with ankylosing spondylitis-related thoracolumbar kyphosis following pedicle subtraction osteotomy.</a> Journal of Neurosurgery Spine. 36 (4), 624-631 (2022).</li><li>Khanna, K., Sabharwal, S. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Spinal+tuberculosis:+A+comprehensive+review+for+the+modern+spine+surgeon.">Spinal tuberculosis: A comprehensive review for the modern spine surgeon.</a> The Spine Journal. 19 (11), 1858-1870 (2019).</li><li>Zhang, H. Q., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Deformed+complex+vertebral+osteotomy+technique+for+management+of+severe+congenital+spinal+angular+kyphotic+deformity.">Deformed complex vertebral osteotomy technique for management of severe congenital spinal angular kyphotic deformity.</a> Orthopaedic Surgery. 13 (3), 1016-1025 (2021).</li><li>Schwab, F., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=The+comprehensive+anatomical+spinal+osteotomy+classification.">The comprehensive anatomical spinal osteotomy classification.</a> Neurosurgery. 74 (1), 112-120 (2014).</li><li>Tarawneh, A. M., Venkatesan, M., Pasku, D., Singh, J., Quraishi, N. A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Impact+of+pedicle+subtraction+osteotomy+on+health-related+quality+of+life+(HRQOL)+measures+in+patients+undergoing+surgery+for+adult+spinal+deformity:+A+systematic+review+and+meta-analysis.">Impact of pedicle subtraction osteotomy on health-related quality of life (HRQOL) measures in patients undergoing surgery for adult spinal deformity: A systematic review and meta-analysis.</a> European Spine Journal. 29 (12), 2953-2959 (2020).</li><li>Kose, K. C., Bozduman, O., Yenigul, A. E., Igrek, S. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Spinal+osteotomies:+Indications,+limits+and+pitfalls.">Spinal osteotomies: Indications, limits and pitfalls.</a> EFORT Open Reviews. 2 (3), 73-82 (2017).</li><li>Liu, X., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Expanded+eggshell+procedure+combined+with+closing-opening+technique+(a+modified+vertebral+column+resection)+for+the+treatment+of+thoracic+and+thoracolumbar+angular+kyphosis.">Expanded eggshell procedure combined with closing-opening technique (a modified vertebral column resection) for the treatment of thoracic and thoracolumbar angular kyphosis.</a> Journal of Neurosurgery: Spine. 23 (1), 42-48 (2015).</li><li>Yang, D. L., Yang, S. D., Chen, Q., Shen, Y., Ding, W. Y. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=The+treatment+evaluation+for+osteoporotic+Kummell+disease+by+modified+posterior+vertebral+column+resection:+Minimum+of+one-year+follow-up.">The treatment evaluation for osteoporotic Kummell disease by modified posterior vertebral column resection: Minimum of one-year follow-up.</a> Medical Science Monitor. 23, 606-612 (2017).</li><li>Fennell, V. S., Palejwala, S., Skoch, J., Stidd, D. A., Baaj, A. A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Freehand+thoracic+pedicle+screw+technique+using+a+uniform+entry+point+and+sagittal+trajectory+for+all+levels:+Preliminary+clinical+experience.">Freehand thoracic pedicle screw technique using a uniform entry point and sagittal trajectory for all levels: Preliminary clinical experience.</a> Journal of Neurosurgery: Spine. 21 (5), 778-784 (2014).</li><li>Wang, H., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Comparison+of+clinical+and+radiological+improvement+between+the+modified+trephine+and+high-speed+drill+as+main+osteotomy+instrument+in+pedicle+subtraction+osteotomy.">Comparison of clinical and radiological improvement between the modified trephine and high-speed drill as main osteotomy instrument in pedicle subtraction osteotomy.</a> Medicine. 94 (45), 2027 (2015).</li><li>Li, X., Ding, W., Zhao, R., Yang, S. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Risk+factors+of+total+blood+loss+and+hidden+blood+loss+in+patients+with+adolescent+idiopathic+scoliosis:+A+retrospective+study.">Risk factors of total blood loss and hidden blood loss in patients with adolescent idiopathic scoliosis: A retrospective study.</a> BioMed Research International. 2022, 9305190 (2022).</li><li>Wang, H., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Unilateral+posterior+vertebral+column+resection+for+severe+thoracolumbar+kyphotic+deformity+caused+by+old+compressive+vertebrae+fracture:+A+technical+improvement.">Unilateral posterior vertebral column resection for severe thoracolumbar kyphotic deformity caused by old compressive vertebrae fracture: A technical improvement.</a> International Journal of Clinical and Experimental Medicine. 8 (3), 3579-3584 (2015).</li><li>Liu, F. Y., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Modified+posterior+vertebral+column+resection+for+Kummell+disease:+Case+report.">Modified posterior vertebral column resection for Kummell disease: Case report.</a> Medicine. 96 (5), 5955 (2017).</li><li>Policicchio, D., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Pedicled+multifidus+muscle+flap+to+treat+inaccessible+dural+tear+in+spine+surgery:+Technical+note+and+preliminary+experience.">Pedicled multifidus muscle flap to treat inaccessible dural tear in spine surgery: Technical note and preliminary experience.</a> World Neurosurgery. 145, 267-277 (2021).</li><li>Yang, C., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Posterior+vertebral+column+resection+in+spinal+deformity:+A+systematic+review.">Posterior vertebral column resection in spinal deformity: A systematic review.</a> European Spine Journal. 25 (8), 2368-2375 (2016).</li><li>Tang, H. Z., Xu, H., Yao, X. D., Lin, S. Q. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Single-stage+posterior+vertebral+column+resection+and+internal+fixation+for+old+fracture-dislocations+of+thoracolumbar+spine:+A+case+series+and+systematic+review.">Single-stage posterior vertebral column resection and internal fixation for old fracture-dislocations of thoracolumbar spine: A case series and systematic review.</a> European Spine Journal. 25 (8), 2497-2513 (2016).</li></ol>

The authors have no conflicts of interest in this research.

The steps of placing the temporary fixation rod and the deformity correction mentioned in the protocol are the critical steps during the surgery. By preserving one side of the pedicle and loading a temporary fixation bar, stability is preserved during the osteotomy procedure. During the surgical progress of the deformity correction, the nerve roots must be protected to prevent serious postoperative neurological complications. If the surgeons are uncertain about the location of the nerve roots, the exposure of the nerve r...

Thoracolumbar kyphotic deformity is a primary or secondary disease generally caused by vertebrae fracture, vertebral body development, ankylosing spondylitis, and spinal tuberculosis1,2,3,4. Severe kyphotic deformity often induces spinal cord compression or severe low back pain. Once conservative treatment becomes ineffective, a surgical approach is necessary due to the complications caused by the deformity. However, the appropriate surgical treatment remains controversial.
The surgical approach to treat severe kyphotic deformity usually needs grade 3 or higher osteotomy5. Pedicle subtraction osteotomy (PSO) is a technique in which a three-column osteotomy can be achieved, which is reported with correction between 30&#176; and 40&#176;6. When the kyphotic deformity is more than 40&#176;, vertebral column resection is recommended, but it can shorten the spine and induce spinal cord bulk7. Partial body and disc resection (BDBO; grade 4) and posterior vertebral column resection (PVCR; grade 5) require complete interception of the anterior and middle columns of the spine, which may cause huge damage to the spine with severe neurologic complications due to spinal instability in the operation or postoperative implant settlement7,8. For general operators, the technique is hard to master, and the surgical damage is enormous for the patients. Thus, a method that is easier to perform with less damage is needed.
In this report, we introduce a refined surgical technique with a modified trephine to treat thoracolumbar kyphosis by removing the vertebral and adjacent discs unilaterally and placing a titanium mesh with autologous bone on the same side. This technique aims to minimize the damage to the patient while achieving good results. In our previous research, the refined surgical procedure showed significantly greater outcomes and reduced the damage to the spine through the preservation of the contralateral pedicle and part of the vertebral body9.

<table border="1" fo:keep-together.within-page="1" fo:keep-with-next.within-page="always">
	<tbody>
		<tr>
			<td>Adhesive</td>
			<td>Biatain</td>
			<td>3420</td>
			<td>12.5 cm x 12.5 cm</td>
		</tr>
		<tr>
			<td>Bipolar electrocoagulation tweezers</td>
			<td>Juan&#39;en Medical Devices Co.Ltd</td>
			<td>BZN-Q-B-S</td>
			<td>1.2 mm x 190 mm</td>
		</tr>
		<tr>
			<td>Bone wax</td>
			<td>ETHICON</td>
			<td>W810T</td>
			<td>2.5g</td>
		</tr>
		<tr>
			<td>Curette</td>
			<td>Qingniu</td>
			<td>20739.01</td>
			<td>300 x &#216;9 x 5&#176;</td>
		</tr>
		<tr>
			<td>Double jointed forceps</td>
			<td>SHINVA</td>
			<td>286920</td>
			<td>240 mm x 8 mm</td>
		</tr>
		<tr>
			<td>High frequency active electrodes</td>
			<td>ZhongBangTianCheng</td>
			<td>GD-BZ</td>
			<td>GD-BZ-J1</td>
		</tr>
		<tr>
			<td>Laminectomy rongeur</td>
			<td>Qingniu</td>
			<td>2054.03</td>
			<td>220 x 3.0 x 130&#176;</td>
		</tr>
		<tr>
			<td>Laminectomy rongeur</td>
			<td>Qingniu</td>
			<td>2058.03</td>
			<td>220 x 5.0 x 130&#176;</td>
		</tr>
		<tr>
			<td>Pedicle screw</td>
			<td>WEGO</td>
			<td>800386545</td>
			<td>6.5 mm x 45 mm</td>
		</tr>
		<tr>
			<td>Pedicle screw</td>
			<td>WEGO</td>
			<td>800386550</td>
			<td>6.5 mm x 50 mm</td>
		</tr>
		<tr>
			<td>Pituitary&#160;rongeur</td>
			<td>Qingniu</td>
			<td>2028.01</td>
			<td>220 mm x 3.0 mm</td>
		</tr>
		<tr>
			<td>Pituitary&#160;rongeur</td>
			<td>Qingniu</td>
			<td>2028.02</td>
			<td>220 mm x 3.0 mm</td>
		</tr>
		<tr>
			<td>Rod</td>
			<td>WEGO</td>
			<td>800386040</td>
			<td>5.5 mm x 500 mm</td>
		</tr>
		<tr>
			<td>Surgical drainage catheter set</td>
			<td>BAINUS MEDICAL</td>
			<td>SY-Fr16-C</td>
			<td>100-400 mL</td>
		</tr>
		<tr>
			<td>Surgical film</td>
			<td>3L</td>
			<td>SP4530</td>
			<td>45 cm x 30 cm</td>
		</tr>
		<tr>
			<td>Titanium&#160;cage</td>
			<td>WEGO</td>
			<td>9051228</td>
			<td>19 mm x 80 mm</td>
		</tr>
		<tr>
			<td>Trephine</td>
			<td>NATON MEDICAL GROUP</td>
			<td>DJD04130</td>
			<td>12 mm/10 mm</td>
		</tr>
	</tbody>
</table>

modified posterior vertebral column resection for patients with thoracolumbar kyphotic deformity

Old compression vertebrae fracture or congenital kyphoscoliosis with abnormal vertebral body development and other diseases that invade the spine may cause severe thoracolumbar kyphotic deformity, often accompanied by intractable low back pain or compression of the spinal cord, leading to severe neurological symptoms or even paralysis. If conservative treatment cannot relieve the symptoms or correct the deformities, surgical treatment is usually needed. For severe kyphotic deformity, reconstruction of the physiological curvature and rigid fixation determine the prognosis of the patients. Osteotomy and orthopedics are the standard procedure for deformities with severe compression of the front and middle column, but the trauma to the patients is high, with a long operation time and massive blood loss. To avoid these disadvantages, we have developed a modified technique to remove the diseased vertebra unilaterally. In this technique, we use a modified trephine to resect the vertebral columns like in the pedicle screw technique by adding a locking instrument that can restrict the trephine to lower the risk of osteotomy and shorten the surgery time and blood loss.

About 330&#176; decompression can be achieved by using the unilateral PVCR technique. The transverse process and the rib head need to be removed to make sure the abduction angle is enough to remove the contralateral bone.
By using the modified trephine, the bone of the diseased vertebrae can be removed easily by rotating it with mild stress. When the trephine is locked, one should pull out the trephine and probe together, and then a cylinder of cancellous bone can be obtained (<strong class="x...

Watch this Scientific Journal Video about Modified Posterior Vertebral Column Resection for Patients with Thoracolumbar Kyphotic Deformity at JoVE.com

Modified Posterior Vertebral Column Resection for Patients with Thoracolumbar Kyphotic Deformity

We describe a modified technique for resecting the posterior vertebral column unilaterally based on a modified trephine for patients with thoracolumbar kyphotic deformity.

Old compression vertebrae fracture or congenital kyphoscoliosis with abnormal vertebral body development and other diseases that invade the spine may ...

This protocol can help surgeons master surgical procedure on a modified technique. Unilateral posterior vertebral column resection with modified trephine which is used to treat thoracolumbar kyphotic deformity. This technique can reduce operation time, blood loss, the trauma to patients during the surgeries and this technique is easy to learn.To begin, make a median dorsal incision centered on the diseased vertebra with a scalpel, covering two vertebral bodies above and below. To ensure the pedicle screw can be placed in, keep the incision length longer than the two vertebrae adjacent to the lesion on each side. Use a scalpel to cut the skin and subcutaneous tissue vertically along the mark.Then, stop the bleeding using bipolar coagulation. Using electrocoagulation electrotome to separate the latissimus dorsi and multifidus muscles along the muscle attachment points until the posterior spinous process and vertebral plate are revealed. Use osteo forceps to remove part of the facet joints of the two vertebrae above and below the lesion until the articular surface is completely exposed.Then, use the positioning needle to confirm the correct position of the pedicle screws under C-ARM guidance. Choose the entry point, 0.3 milliliters coddle to the junction of the transverse process in the thoracic vertebra. The entry point of the lumbar vertebra is the intersection of the horizontal line of the transverse processes midpoint and the vertical line of the superior articular process.Insert eight pedicle screws bilaterally in the upper and lower segments using a reaming probe to expand the path. Depending on the disease, insert another pedicle screw on one side of the lesioned segment. If the patient suffers from osteoporosis, use bone cement injectable cannulated pedicle screws to strengthen the vertebral bodies.Place a temporary fixation rod opposite the osteotomy side on the pedicle screw caps and fasten the nuts. Then use a rongeur to excise the lesion's segments spinous process. Next, use the laminectomy rongeur to remove the lamina adjacent to the spinous and inferior articular processes on the osteotomy side.Following these procedures, use the rongeur to cut off the transverse process on the same side. Perform the osteotomy in the surgery using a modified trephine. First, insert the pedicle probe into the lesioned vertebra.Then use a modified trephine to remove the bone by twisting the handle into the vertebra. When the top of the trephine reaches the tip of the probe, the locking instrument will restrict its movement and prevent the serrated top from injuring the anterior tissue. Hold on to the trephine and probe, then slowly pull them out and collect the cancellous bone in the trephine for later use.Then repeat the same procedure to remove the bone quickly. Sometimes the bone may not come out with the trephine. Use a nucleus pulposus clamp to remove it.Remove the contralateral bone by changing the angle of the probe and ensuring that the trephine does not injure the nerves, preserving the vertebral arch and part of the bone. Next, use the laminectomy rongeur and nucleus pulposus clamp to remove the remaining small cancellous bone fragments and discs, then, use a curette to scrape the upper and lower end plate cartilage. The osteotomy will be complete when the space is large enough to implant the titanium mesh.Under the isolation of the dura by the nerve dissector, use the reverse curette and osteotome to remove the posterior wall of the vertebra. Once the compression to the spinal cord is relieved, gently pull the spinal cord into a position where the titanium cage can be safely implanted. Be careful not to damage the spinal dura mater to avoid cerebrospinal fluid leakage.Remove the temporary fixation bar and place an orthopedic rod pre-corrected to the proper curvature. Screw and fasten the nuts on the opposite side of the osteotomy. Fill an appropriately sized titanium cage with the amputated autologous bone.Then place it in the correct position to prevent forward flexion of the spine. Implant the autologous fragmented bones, peripherally. Place another fixing rod with the same curvature as the rod placed previously on the osteotomy side and screw and fasten the nuts.Use a large amount of saline to flush the operative field and stop active bleeding with bipolar electrocoagulation. Then, use gelatin sponges to fill the void and insert one or two closed suction drains to prevent postoperative hematoma. Close the incision layer by layer and ensure that each layer is not sutured to the drains.Use interrupted absorbable sutures to suture the muscle and continuous absorbable sutures to close the fascia. Use a skin stapler to close the skin. Combining the unilateral PVCR technique and modified trephine allowed removal of the lesions and rebuilding of spinal stability for patients with Kummell disease, especially for patients with kyphotic deformity and obvious nerve-oppressed symptoms.The nerve roots and the spinal cord must be protected to prevent severe posterior neurological complications during the surgery.

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2.0K 조회수.  The Third Hospital of Hebei Medical University. 이 프로토콜은 외과의가 수정된 기술로 수술 절차를 마스터하는 데 도움이 될 수 있습니다. 흉요추 후만 기형을 치료하는 데 사용되는 변형된 트레핀을 사용한 편측 후방 척추 절제술. 이 기술은 수술 시간, 출혈, 수술 중 환자의 외상을 줄일 수 있으며 이 기술은 배우기 쉽습니다.시작하려면 메스로 병든 척추를 중심으로 중앙 등쪽 절개를 하고 위와 아래 두 개의 척추?...