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Functional recovery following traumatic spinal cord injury mediated by a unique polymer scaffold seeded with neural stem cells.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2002 | Pubmed ID: 11867737
Transplanted clonal neural stem-like cells respond to remote photic stimulation following incorporation within the suprachiasmatic nucleus.
Experimental neurology Apr, 2002 | Pubmed ID: 11922658
Limitations in brain repair.
Nature medicine Sep, 2002 | Pubmed ID: 12205449
Transplanted neural stem cells survive, differentiate, and improve neurological motor function after experimental traumatic brain injury.
Neurosurgery Oct, 2002 | Pubmed ID: 12234415
Neural stem cells display an inherent mechanism for rescuing dysfunctional neurons.
Nature biotechnology Nov, 2002 | Pubmed ID: 12379867
The injured brain interacts reciprocally with neural stem cells supported by scaffolds to reconstitute lost tissue.
Nature biotechnology Nov, 2002 | Pubmed ID: 12379868
Neural stem cells spontaneously express dopaminergic traits after transplantation into the intact or 6-hydroxydopamine-lesioned rat.
Experimental neurology Sep, 2002 | Pubmed ID: 12429210
Neural stem cells for CNS repair: state of the art and future directions.
Advances in experimental medicine and biology , 2002 | Pubmed ID: 12614070
Genetic programs and responses of neural stem/progenitor cells during demyelination: potential insights into repair mechanisms in multiple sclerosis.
Physiological genomics Aug, 2003 | Pubmed ID: 12923300
Neural stem cell biology may be well suited for improving brain tumor therapies.
Cancer journal (Sudbury, Mass.) May-Jun, 2003 | Pubmed ID: 12952304
Realistic prospects for stem cell therapeutics.
Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program , 2003 | Pubmed ID: 14633792
Constitutive EGFR signaling confers a motile phenotype to neural stem cells.
Molecular and cellular neurosciences Dec, 2003 | Pubmed ID: 14697673
Fate of multipotent neural precursor cells transplanted into mouse retina selectively depleted of retinal ganglion cells.
Experimental neurology Mar, 2004 | Pubmed ID: 14980806
Minocycline inhibits contusion-triggered mitochondrial cytochrome c release and mitigates functional deficits after spinal cord injury.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2004 | Pubmed ID: 14981254
Reality and immortality--neural stem cells for therapies.
Nature biotechnology Mar, 2004 | Pubmed ID: 14990948
Taking stock and planning for the next decade: realistic prospects for stem cell therapies for the nervous system.
Journal of neuroscience research Apr, 2004 | Pubmed ID: 15048913
Neural stem/progenitor cells express costimulatory molecules that are differentially regulated by inflammatory and apoptotic stimuli.
The American journal of pathology May, 2004 | Pubmed ID: 15111308
Stem cells: cross-talk and developmental programs.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences May, 2004 | Pubmed ID: 15293810
Differentiation and tropic/trophic effects of exogenous neural precursors in the adult spinal cord.
The Journal of comparative neurology Nov, 2004 | Pubmed ID: 15514921
Neural stem cells protect against glutamate-induced excitotoxicity and promote survival of injured motor neurons through the secretion of neurotrophic factors.
Molecular and cellular neurosciences Nov, 2004 | Pubmed ID: 15519246
Directed migration of neural stem cells to sites of CNS injury by the stromal cell-derived factor 1alpha/CXC chemokine receptor 4 pathway.
Proceedings of the National Academy of Sciences of the United States of America Dec, 2004 | Pubmed ID: 15608062
A review and rationale for the use of cellular transplantation as a therapeutic strategy for traumatic brain injury.
Journal of neurotrauma Nov, 2004 | Pubmed ID: 15684646
Neural stem cells implanted into MPTP-treated monkeys increase the size of endogenous tyrosine hydroxylase-positive cells found in the striatum: a return to control measures.
Cell transplantation , 2005 | Pubmed ID: 15929553
Expression profile of an operationally-defined neural stem cell clone.
Experimental neurology Aug, 2005 | Pubmed ID: 15992799
A role for stem cell biology in the physiological and pathological aspects of aging.
Journal of the American Geriatrics Society Sep, 2005 | Pubmed ID: 16131354
Caspase-mediated cell death predominates following engraftment of neural progenitor cells into traumatically injured rat brain.
Brain research Dec, 2005 | Pubmed ID: 16309635
Gene therapy: can neural stem cells deliver?
Nature reviews. Neuroscience Jan, 2006 | Pubmed ID: 16371952
Therapeutic effects of clenbuterol in a murine model of amyotrophic lateral sclerosis.
Neuroscience letters Apr 10-17, 2006 | Pubmed ID: 16388902
Networks of gold nanoparticles and bacteriophage as biological sensors and cell-targeting agents.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2006 | Pubmed ID: 16434473
Beyond fraud--stem-cell research continues.
The New England journal of medicine Jan, 2006 | Pubmed ID: 16436761
Can science resolve the ethical impasse in stem cell research?
Nature biotechnology Apr, 2006 | Pubmed ID: 16601717
Neural progenitor cells engineered to secrete GDNF show enhanced survival, neuronal differentiation and improve cognitive function following traumatic brain injury.
The European journal of neuroscience Apr, 2006 | Pubmed ID: 16630059
Purkinje neuron degeneration in nervous (nr) mutant mice is mediated by a metabolic pathway involving excess tissue plasminogen activator.
Proceedings of the National Academy of Sciences of the United States of America May, 2006 | Pubmed ID: 16682647
Neural stem cells as novel cancer therapeutic vehicles.
European journal of cancer (Oxford, England : 1990) Jun, 2006 | Pubmed ID: 16697638
Neural stem cells may be uniquely suited for combined gene therapy and cell replacement: Evidence from engraftment of Neurotrophin-3-expressing stem cells in hypoxic-ischemic brain injury.
Experimental neurology May, 2006 | Pubmed ID: 16714016
Human neurospheres derived from the fetal central nervous system are regionally and temporally specified but are not committed.
Experimental neurology May, 2006 | Pubmed ID: 16714017
Acute injury directs the migration, proliferation, and differentiation of solid organ stem cells: evidence from the effect of hypoxia-ischemia in the CNS on clonal "reporter" neural stem cells.
Experimental neurology May, 2006 | Pubmed ID: 16737696
Special issue: the intersection of stem/progenitor cell biology and hypoxic-ischemic cerebral injury/stroke.
Experimental neurology May, 2006 | Pubmed ID: 16798271
Intrinsic resistance of neural stem cells to toxic metabolites may make them well suited for cell non-autonomous disorders: evidence from a mouse model of Krabbe leukodystrophy.
Journal of neurochemistry Jun, 2006 | Pubmed ID: 16805770
Cryopreservation by slow cooling with DMSO diminished production of Oct-4 pluripotency marker in human embryonic stem cells.
Cryobiology Oct, 2006 | Pubmed ID: 16839540
Neural stem cells rescue nervous purkinje neurons by restoring molecular homeostasis of tissue plasminogen activator and downstream targets.
The Journal of neuroscience : the official journal of the Society for Neuroscience Jul, 2006 | Pubmed ID: 16870729
Defining the actual sensitivity and specificity of the neurosphere assay in stem cell biology.
Nature methods Oct, 2006 | Pubmed ID: 16990812
Adhesive interactions between human neural stem cells and inflamed human vascular endothelium are mediated by integrins.
Stem cells (Dayton, Ohio) Nov, 2006 | Pubmed ID: 17071855
The leading edge of stem cell therapeutics.
Annual review of medicine , 2007 | Pubmed ID: 17100553
Neural stem cell transplant survival in brains of mice: assessing the effect of immunity and ischemia by using real-time bioluminescent imaging.
Radiology Dec, 2006 | Pubmed ID: 17114629
Exploring common ground in the stem cell ethical debate--a perspective for scientists: introduction to this special issue of stem cell reviews.
Stem cell reviews Dec, 2005 | Pubmed ID: 17142867
Isolation of amniotic stem cell lines with potential for therapy.
Nature biotechnology Jan, 2007 | Pubmed ID: 17206138
Immunomodulatory neural stem cells for brain tumour therapy.
Expert opinion on biological therapy Dec, 2006 | Pubmed ID: 17223735
Injection of mouse and human neural stem cells into neonatal Niemann-Pick A model mice.
Brain research Apr, 2007 | Pubmed ID: 17289003
Stem cells act through multiple mechanisms to benefit mice with neurodegenerative metabolic disease.
Nature medicine Apr, 2007 | Pubmed ID: 17351625
Physical activity-mediated functional recovery after spinal cord injury: potential roles of neural stem cells.
Regenerative medicine Nov, 2006 | Pubmed ID: 17465758
Large animal models are critical for rationally advancing regenerative therapies.
Regenerative medicine Jul, 2006 | Pubmed ID: 17465832
A novel, immortal, and multipotent human neural stem cell line generating functional neurons and oligodendrocytes.
Stem cells (Dayton, Ohio) Sep, 2007 | Pubmed ID: 17556596
Behavioral improvement in a primate Parkinson's model is associated with multiple homeostatic effects of human neural stem cells.
Proceedings of the National Academy of Sciences of the United States of America Jul, 2007 | Pubmed ID: 17586681
Neural stem cells injected into the sound-damaged cochlea migrate throughout the cochlea and express markers of hair cells, supporting cells, and spiral ganglion cells.
Hearing research Oct, 2007 | Pubmed ID: 17659854
Neural stem cell implantation extends life in Niemann-Pick C1 mice.
Journal of applied genetics , 2007 | Pubmed ID: 17666780
Neural progenitor cell transplantation and imaging in a large animal model.
Neuroscience research Nov, 2007 | Pubmed ID: 17897743
Genetic modification of neural stem cells.
Molecular therapy : the journal of the American Society of Gene Therapy Mar, 2008 | Pubmed ID: 18253153
Stem cell-mediated regeneration of the intervertebral disc: cellular and molecular challenge.
Neurosurgical focus , 2008 | Pubmed ID: 18341398
Brain tumor stem cells and the tumor microenvironmen.
Neurosurgical focus , 2008 | Pubmed ID: 18341404
Quo vadis brain repair? A long axonal journey in the adult CNS.
Cell stem cell Oct, 2007 | Pubmed ID: 18371370
Human neural stem cells migrate along the nigrostriatal pathway in a primate model of Parkinson's disease.
Experimental neurology Jun, 2008 | Pubmed ID: 18394605
Neural stem cell transplantation in mouse brain.
Current protocols in neuroscience / editorial board, Jacqueline N. Crawley ... [et al.] Jan, 2008 | Pubmed ID: 18428671
Inflammation as a matchmaker: revisiting cell fusion.
Nature cell biology May, 2008 | Pubmed ID: 18454127
Neural stem cell delivery to the spinal cord in an ovine model of fetal surgery for spina bifida.
Surgery Sep, 2008 | Pubmed ID: 18707035
Preparation of autogenic human feeder cells for growth of human embryonic stem cells.
Current protocols in stem cell biology Mar, 2008 | Pubmed ID: 18770638
Neural stem/progenitor cells modulate immune responses by suppressing T lymphocytes with nitric oxide and prostaglandin E2.
Experimental neurology Mar, 2009 | Pubmed ID: 19109951
Neural precursor cell lines promote neurite branching.
The International journal of neuroscience , 2009 | Pubmed ID: 19116829
Role of monocyte chemoattractant protein-1 (MCP-1/CCL2) in migration of neural progenitor cells toward glial tumors.
Journal of neuroscience research May, 2009 | Pubmed ID: 19125409
Discovery of a functional protein complex of netrin-4, laminin gamma1 chain, and integrin alpha6beta1 in mouse neural stem cells.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2009 | Pubmed ID: 19193855
Neuroimaging as a basis for rational stem cell therapy.
Pediatric neurology Mar, 2009 | Pubmed ID: 19218036
The dynamics of long-term transgene expression in engrafted neural stem cells.
The Journal of comparative neurology Jul, 2009 | Pubmed ID: 19399895
Long-term multilayer adherent network (MAN) expansion, maintenance, and characterization, chemical and genetic manipulation, and transplantation of human fetal forebrain neural stem cells.
Current protocols in stem cell biology May, 2009 | Pubmed ID: 19455542
Maintaining and engineering neural stem cells for delivery of genetically encoded therapy to brain tumors.
Methods in molecular biology (Clifton, N.J.) , 2009 | Pubmed ID: 19582432
Neural stem cell transplantation benefits a monogenic neurometabolic disorder during the symptomatic phase of disease.
Stem cells (Dayton, Ohio) Sep, 2009 | Pubmed ID: 19591217
Phosphoproteomic analysis of human embryonic stem cells.
Cell stem cell Aug, 2009 | Pubmed ID: 19664994
Culture system for rodent and human oligodendrocyte specification, lineage progression, and maturation.
Current protocols in stem cell biology Sep, 2009 | Pubmed ID: 19725014
A safer stem cell: on guard against cancer.
Nature medicine Sep, 2009 | Pubmed ID: 19734873
Cross-talk between stem cells and the dysfunctional brain is facilitated by manipulating the niche: evidence from an adhesion molecule.
Stem cells (Dayton, Ohio) Nov, 2009 | Pubmed ID: 19785036
Important precautions when deriving patient-specific neural elements from pluripotent cells.
Cytotherapy , 2009 | Pubmed ID: 19903095
The transcriptional network for mesenchymal transformation of brain tumours.
Nature Jan, 2010 | Pubmed ID: 20032975
Screening the mammalian extracellular proteome for regulators of embryonic human stem cell pluripotency.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2010 | Pubmed ID: 20133595
Communication via gap junctions underlies early functional and beneficial interactions between grafted neural stem cells and the host.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2010 | Pubmed ID: 20147621
Derivation of vasculature from embryonic stem cells.
Current protocols in stem cell biology Mar, 2010 | Pubmed ID: 20200855
Microarray-based transcriptional and epigenetic profiling of matrix metalloproteinases, collagens, and related genes in cancer.
The Journal of biological chemistry Jun, 2010 | Pubmed ID: 20404328
Culture and manipulation of neural stem cells.
Advances in experimental medicine and biology , 2010 | Pubmed ID: 20455492
Nna1 mediates Purkinje cell dendritic development via lysyl oxidase propeptide and NF-κB signaling.
Neuron Oct, 2010 | Pubmed ID: 20920790
Early acquisition of neural crest competence during hESCs neuralization.
PloS one , 2010 | Pubmed ID: 21085480
Neurotransplantation of stem cells genetically modified to express human dopamine transporter reduces alcohol consumption.
Stem cell research & therapy , 2010 | Pubmed ID: 21122109
Self-renewal induced efficiently, safely, and effective therapeutically with one regulatable gene in a human somatic progenitor cell.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2011 | Pubmed ID: 21378266
Dorsomorphin promotes human embryonic stem cell self-renewal.
Angewandte Chemie (International ed. in English) Apr, 2011 | Pubmed ID: 21384475
Long-term magnetic resonance imaging of stem cells in neonatal ischemic injury.
Annals of neurology Feb, 2011 | Pubmed ID: 21387373
The risk of putting something where it does not belong: mesenchymal stem cells produce masses in the brain.
Experimental neurology Jul, 2011 | Pubmed ID: 21420402
Overexpression of Basic Helix-Loop-Helix Transcription Factors Enhances Neuronal Differentiation of Fetal Human Neural Progenitor Cells in Various Ways.
Stem cells and development Jul, 2011 | Pubmed ID: 21561385
The intricate dance between repair and inflammation: introduction to special issue.
Experimental neurology Jul, 2011 | Pubmed ID: 21596040
DMSO-Free Programmed Cryopreservation of Fully Dissociated and Adherent Human Induced Pluripotent Stem Cells.
Stem cells international , 2011 | Pubmed ID: 21716669
Modeling complex neuropsychiatric disorders with human induced pluripotent stem cells.
Current opinion in pharmacology Oct, 2011 | Pubmed ID: 21723195
Phosphoproteomic Analysis: An Emerging Role in Deciphering Cellular Signaling in Human Embryonic Stem Cells and Their Differentiated Derivatives.
Stem cell reviews Oct, 2011 | Pubmed ID: 22009073
Quantitative Analysis of Human Pluripotency and Neural Specification by In-Depth (Phospho)Proteomic Profiling.
Stem cell reports 09, 2016 | Pubmed ID: 27569059
Modeling Complex Neurological Diseases with Stem Cells: A Study of Bipolar Disorder.
Results and problems in cell differentiation , 2018 | Pubmed ID: 30209664
Induced pluripotency and spontaneous reversal of cellular aging in supercentenarian donor cells.
Biochemical and biophysical research communications 05, 2020 | Pubmed ID: 32115145
Quantitative assessment of barriers to the clinical development and adoption of cellular therapies: A pilot study.
Journal of tissue engineering , 2014 | Pubmed ID: 25383173
Generating iPSCs: translating cell reprogramming science into scalable and robust biomanufacturing strategies.
Cell stem cell Jan, 2015 | Pubmed ID: 25575079
Enabling consistency in pluripotent stem cell-derived products for research and development and clinical applications through material standards.
Stem cells translational medicine Mar, 2015 | Pubmed ID: 25650438
hESC Differentiation toward an Autonomic Neuronal Cell Fate Depends on Distinct Cues from the Co-Patterning Vasculature.
Stem cell reports Jun, 2015 | Pubmed ID: 26004631
Probing the lithium-response pathway in hiPSCs implicates the phosphoregulatory set-point for a cytoskeletal modulator in bipolar pathogenesis.
Proceedings of the National Academy of Sciences of the United States of America 05, 2017 | Pubmed ID: 28500272
Finding a new purpose for old drugs.
Science (New York, N.Y.) Sep, 2017 | Pubmed ID: 28860370
Stem Cell Composition of Umbilical Cord Blood Following Milking Compared with Delayed Clamping of the Cord Appears Better Suited for Promoting Hematopoiesis.
The Journal of pediatrics Jan, 2020 | Pubmed ID: 31471115
The Evolution of Stem Cells, Disease Modeling, and Drug Discovery for Neurological Disorders.
Stem cells and development Sep, 2020 | Pubmed ID: 32024446
Discovery of suppressors of CRMP2 phosphorylation reveals compounds that mimic the behavioral effects of lithium on amphetamine-induced hyperlocomotion.
Translational psychiatry Feb, 2020 | Pubmed ID: 32094324
A Biomarker for Predicting Responsiveness to Stem Cell Therapy Based on Mechanism-of-Action: Evidence from Cerebral Injury.
Cell reports May, 2020 | Pubmed ID: 32402283
Generation of Complete Multi-Cell Type Lung Organoids From Human Embryonic and Patient-Specific Induced Pluripotent Stem Cells for Infectious Disease Modeling and Therapeutics Validation.
Current protocols in stem cell biology 09, 2020 | Pubmed ID: 32640120
Deriving Keratinocyte Progenitor Cells and Keratinocytes from Human-Induced Pluripotent Stem Cells.
Current protocols in stem cell biology Sep, 2020 | Pubmed ID: 32744801
"Reprogram Enablement" as an Assay for Identifying Early Oncogenic Pathways by Their Ability to Allow Neoplastic Cells to Reacquire an Epiblast State.
Stem cell reports Sep, 2020 | Pubmed ID: 32795421
Chemical mutagenesis of a GPCR ligand: Detoxifying "inflammo-attraction" to direct therapeutic stem cell migration.
Proceedings of the National Academy of Sciences of the United States of America Dec, 2020 | Pubmed ID: 33219123
Valproate reverses mania-like behaviors in mice via preferential targeting of HDAC2.
Molecular psychiatry Aug, 2021 | Pubmed ID: 33235333
Strategies and Progress in CXCR4-Targeted Anti-Human Immunodeficiency Virus (HIV) Therapeutic Development.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America Sep, 2021 | Pubmed ID: 33624027
Meningeal Multipotent Cells: A Hidden Target for CNS Repair?
Neuromolecular medicine Sep, 2021 | Pubmed ID: 33893971
A Tool for Accurate Stoichiometric Composition of Cryopreservative Media for Fetal and Induced Pluripotent Stem Cell-Derived Human Neural Stem Cells.
Current protocols May, 2021 | Pubmed ID: 33950578
The Developmental & Molecular Requirements for Ensuring that Human Pluripotent Stem Cell-Derived Hair Follicle Bulge Stem Cells Have Acquired Competence for Hair Follicle Generation Following Transplantation.
Cell transplantation , 2021 | Pubmed ID: 34053245
Clinical evidence that a dysregulated master neural network modulator may aid in diagnosing schizophrenia.
Proceedings of the National Academy of Sciences of the United States of America Aug, 2021 | Pubmed ID: 34330827
Protocol to optimize the Rice-Vannucci rat pup model of perinatal asphyxia to ensure predictable hypoxic-ischemic cerebral lesions.
STAR protocols Jun, 2024 | Pubmed ID: 38852156
A therapy for suppressing canonical and noncanonical SARS-CoV-2 viral entry and an intrinsic intrapulmonary inflammatory response.
Proceedings of the National Academy of Sciences of the United States of America Jul, 2024 | Pubmed ID: 39028694
Exercise your graft - An important lesson for cell replacement therapy for Parkinson's disease.
Experimental neurology Dec, 2024 | Pubmed ID: 39631719
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