Evan Y. Snyder

Functional recovery following traumatic spinal cord injury mediated by a unique polymer scaffold seeded with neural stem cells.

Transplanted clonal neural stem-like cells respond to remote photic stimulation following incorporation within the suprachiasmatic nucleus.

Limitations in brain repair.

Transplanted neural stem cells survive, differentiate, and improve neurological motor function after experimental traumatic brain injury.

Neural stem cells display an inherent mechanism for rescuing dysfunctional neurons.

The injured brain interacts reciprocally with neural stem cells supported by scaffolds to reconstitute lost tissue.

Neural stem cells spontaneously express dopaminergic traits after transplantation into the intact or 6-hydroxydopamine-lesioned rat.

Neural stem cells for CNS repair: state of the art and future directions.

Genetic programs and responses of neural stem/progenitor cells during demyelination: potential insights into repair mechanisms in multiple sclerosis.

Neural stem cell biology may be well suited for improving brain tumor therapies.

Realistic prospects for stem cell therapeutics.

Constitutive EGFR signaling confers a motile phenotype to neural stem cells.

Fate of multipotent neural precursor cells transplanted into mouse retina selectively depleted of retinal ganglion cells.

Minocycline inhibits contusion-triggered mitochondrial cytochrome c release and mitigates functional deficits after spinal cord injury.

Reality and immortality--neural stem cells for therapies.

Taking stock and planning for the next decade: realistic prospects for stem cell therapies for the nervous system.

Neural stem/progenitor cells express costimulatory molecules that are differentially regulated by inflammatory and apoptotic stimuli.

Stem cells: cross-talk and developmental programs.

Differentiation and tropic/trophic effects of exogenous neural precursors in the adult spinal cord.

Neural stem cells protect against glutamate-induced excitotoxicity and promote survival of injured motor neurons through the secretion of neurotrophic factors.

Directed migration of neural stem cells to sites of CNS injury by the stromal cell-derived factor 1alpha/CXC chemokine receptor 4 pathway.

A review and rationale for the use of cellular transplantation as a therapeutic strategy for traumatic brain injury.

Neural stem cells implanted into MPTP-treated monkeys increase the size of endogenous tyrosine hydroxylase-positive cells found in the striatum: a return to control measures.

Expression profile of an operationally-defined neural stem cell clone.

A role for stem cell biology in the physiological and pathological aspects of aging.

Caspase-mediated cell death predominates following engraftment of neural progenitor cells into traumatically injured rat brain.

Gene therapy: can neural stem cells deliver?

Therapeutic effects of clenbuterol in a murine model of amyotrophic lateral sclerosis.

Networks of gold nanoparticles and bacteriophage as biological sensors and cell-targeting agents.

Beyond fraud--stem-cell research continues.

Can science resolve the ethical impasse in stem cell research?

Neural progenitor cells engineered to secrete GDNF show enhanced survival, neuronal differentiation and improve cognitive function following traumatic brain injury.

Purkinje neuron degeneration in nervous (nr) mutant mice is mediated by a metabolic pathway involving excess tissue plasminogen activator.

Neural stem cells as novel cancer therapeutic vehicles.

Neural stem cells may be uniquely suited for combined gene therapy and cell replacement: Evidence from engraftment of Neurotrophin-3-expressing stem cells in hypoxic-ischemic brain injury.

Human neurospheres derived from the fetal central nervous system are regionally and temporally specified but are not committed.

Acute injury directs the migration, proliferation, and differentiation of solid organ stem cells: evidence from the effect of hypoxia-ischemia in the CNS on clonal "reporter" neural stem cells.

Special issue: the intersection of stem/progenitor cell biology and hypoxic-ischemic cerebral injury/stroke.

Intrinsic resistance of neural stem cells to toxic metabolites may make them well suited for cell non-autonomous disorders: evidence from a mouse model of Krabbe leukodystrophy.

Cryopreservation by slow cooling with DMSO diminished production of Oct-4 pluripotency marker in human embryonic stem cells.

Neural stem cells rescue nervous purkinje neurons by restoring molecular homeostasis of tissue plasminogen activator and downstream targets.

Defining the actual sensitivity and specificity of the neurosphere assay in stem cell biology.

Adhesive interactions between human neural stem cells and inflamed human vascular endothelium are mediated by integrins.

The leading edge of stem cell therapeutics.

Neural stem cell transplant survival in brains of mice: assessing the effect of immunity and ischemia by using real-time bioluminescent imaging.

Exploring common ground in the stem cell ethical debate--a perspective for scientists: introduction to this special issue of stem cell reviews.

Isolation of amniotic stem cell lines with potential for therapy.

Immunomodulatory neural stem cells for brain tumour therapy.

Injection of mouse and human neural stem cells into neonatal Niemann-Pick A model mice.

Stem cells act through multiple mechanisms to benefit mice with neurodegenerative metabolic disease.

Physical activity-mediated functional recovery after spinal cord injury: potential roles of neural stem cells.

Large animal models are critical for rationally advancing regenerative therapies.

A novel, immortal, and multipotent human neural stem cell line generating functional neurons and oligodendrocytes.

Behavioral improvement in a primate Parkinson's model is associated with multiple homeostatic effects of human neural stem cells.

Neural stem cells injected into the sound-damaged cochlea migrate throughout the cochlea and express markers of hair cells, supporting cells, and spiral ganglion cells.

Neural stem cell implantation extends life in Niemann-Pick C1 mice.

Neural progenitor cell transplantation and imaging in a large animal model.

Genetic modification of neural stem cells.

Stem cell-mediated regeneration of the intervertebral disc: cellular and molecular challenge.

Brain tumor stem cells and the tumor microenvironmen.

Quo vadis brain repair? A long axonal journey in the adult CNS.

Human neural stem cells migrate along the nigrostriatal pathway in a primate model of Parkinson's disease.

Neural stem cell transplantation in mouse brain.

Inflammation as a matchmaker: revisiting cell fusion.

Neural stem cell delivery to the spinal cord in an ovine model of fetal surgery for spina bifida.

Preparation of autogenic human feeder cells for growth of human embryonic stem cells.

Neural stem/progenitor cells modulate immune responses by suppressing T lymphocytes with nitric oxide and prostaglandin E2.

Neural precursor cell lines promote neurite branching.

Role of monocyte chemoattractant protein-1 (MCP-1/CCL2) in migration of neural progenitor cells toward glial tumors.

Discovery of a functional protein complex of netrin-4, laminin gamma1 chain, and integrin alpha6beta1 in mouse neural stem cells.

Neuroimaging as a basis for rational stem cell therapy.

The dynamics of long-term transgene expression in engrafted neural stem cells.

Long-term multilayer adherent network (MAN) expansion, maintenance, and characterization, chemical and genetic manipulation, and transplantation of human fetal forebrain neural stem cells.

Maintaining and engineering neural stem cells for delivery of genetically encoded therapy to brain tumors.

Neural stem cell transplantation benefits a monogenic neurometabolic disorder during the symptomatic phase of disease.

Phosphoproteomic analysis of human embryonic stem cells.

Culture system for rodent and human oligodendrocyte specification, lineage progression, and maturation.

A safer stem cell: on guard against cancer.

Cross-talk between stem cells and the dysfunctional brain is facilitated by manipulating the niche: evidence from an adhesion molecule.

Important precautions when deriving patient-specific neural elements from pluripotent cells.

The transcriptional network for mesenchymal transformation of brain tumours.

Screening the mammalian extracellular proteome for regulators of embryonic human stem cell pluripotency.

Communication via gap junctions underlies early functional and beneficial interactions between grafted neural stem cells and the host.

Derivation of vasculature from embryonic stem cells.

Microarray-based transcriptional and epigenetic profiling of matrix metalloproteinases, collagens, and related genes in cancer.

Culture and manipulation of neural stem cells.

Nna1 mediates Purkinje cell dendritic development via lysyl oxidase propeptide and NF-κB signaling.

Early acquisition of neural crest competence during hESCs neuralization.

Neurotransplantation of stem cells genetically modified to express human dopamine transporter reduces alcohol consumption.

Self-renewal induced efficiently, safely, and effective therapeutically with one regulatable gene in a human somatic progenitor cell.

Dorsomorphin promotes human embryonic stem cell self-renewal.

Long-term magnetic resonance imaging of stem cells in neonatal ischemic injury.

The risk of putting something where it does not belong: mesenchymal stem cells produce masses in the brain.

Overexpression of Basic Helix-Loop-Helix Transcription Factors Enhances Neuronal Differentiation of Fetal Human Neural Progenitor Cells in Various Ways.

The intricate dance between repair and inflammation: introduction to special issue.

DMSO-Free Programmed Cryopreservation of Fully Dissociated and Adherent Human Induced Pluripotent Stem Cells.

Modeling complex neuropsychiatric disorders with human induced pluripotent stem cells.

Phosphoproteomic Analysis: An Emerging Role in Deciphering Cellular Signaling in Human Embryonic Stem Cells and Their Differentiated Derivatives.

Quantitative Analysis of Human Pluripotency and Neural Specification by In-Depth (Phospho)Proteomic Profiling.

Modeling Complex Neurological Diseases with Stem Cells: A Study of Bipolar Disorder.

Induced pluripotency and spontaneous reversal of cellular aging in supercentenarian donor cells.

Quantitative assessment of barriers to the clinical development and adoption of cellular therapies: A pilot study.

Generating iPSCs: translating cell reprogramming science into scalable and robust biomanufacturing strategies.

Enabling consistency in pluripotent stem cell-derived products for research and development and clinical applications through material standards.

hESC Differentiation toward an Autonomic Neuronal Cell Fate Depends on Distinct Cues from the Co-Patterning Vasculature.

Probing the lithium-response pathway in hiPSCs implicates the phosphoregulatory set-point for a cytoskeletal modulator in bipolar pathogenesis.

Finding a new purpose for old drugs.

Stem Cell Composition of Umbilical Cord Blood Following Milking Compared with Delayed Clamping of the Cord Appears Better Suited for Promoting Hematopoiesis.

The Evolution of Stem Cells, Disease Modeling, and Drug Discovery for Neurological Disorders.

Discovery of suppressors of CRMP2 phosphorylation reveals compounds that mimic the behavioral effects of lithium on amphetamine-induced hyperlocomotion.

A Biomarker for Predicting Responsiveness to Stem Cell Therapy Based on Mechanism-of-Action: Evidence from Cerebral Injury.

Generation of Complete Multi-Cell Type Lung Organoids From Human Embryonic and Patient-Specific Induced Pluripotent Stem Cells for Infectious Disease Modeling and Therapeutics Validation.

Deriving Keratinocyte Progenitor Cells and Keratinocytes from Human-Induced Pluripotent Stem Cells.

"Reprogram Enablement" as an Assay for Identifying Early Oncogenic Pathways by Their Ability to Allow Neoplastic Cells to Reacquire an Epiblast State.

Chemical mutagenesis of a GPCR ligand: Detoxifying "inflammo-attraction" to direct therapeutic stem cell migration.

Valproate reverses mania-like behaviors in mice via preferential targeting of HDAC2.

Strategies and Progress in CXCR4-Targeted Anti-Human Immunodeficiency Virus (HIV) Therapeutic Development.

Meningeal Multipotent Cells: A Hidden Target for CNS Repair?

A Tool for Accurate Stoichiometric Composition of Cryopreservative Media for Fetal and Induced Pluripotent Stem Cell-Derived Human Neural Stem Cells.

The Developmental & Molecular Requirements for Ensuring that Human Pluripotent Stem Cell-Derived Hair Follicle Bulge Stem Cells Have Acquired Competence for Hair Follicle Generation Following Transplantation.

Clinical evidence that a dysregulated master neural network modulator may aid in diagnosing schizophrenia.

Protocol to optimize the Rice-Vannucci rat pup model of perinatal asphyxia to ensure predictable hypoxic-ischemic cerebral lesions.

A therapy for suppressing canonical and noncanonical SARS-CoV-2 viral entry and an intrinsic intrapulmonary inflammatory response.

Exercise your graft - An important lesson for cell replacement therapy for Parkinson's disease.