Chapter 23
Drugs for Chronic Bowel Disorders
Distúrbios intestinais crônicos: introdução
Chronic bowel disorders are long-term medical conditions affecting the digestive tract, including disorders such as irritable bowel syndrome or IBS and ...
Medicamentos para o tratamento da SII com predominância de diarreia
Diarrhea-predominant irritable bowel syndrome or IBS-D, is characterized by chronic abdominal pain and diarrhea.
Effective IBS-D management involves ...
Medicamentos para o tratamento da SII com predominância de constipação
Irritable bowel syndrome with constipation or IBS-C, is a recurring digestive disorder characterized by abdominal pain and infrequent bowel movements.
...
Medicamentos para o tratamento da colite ulcerativa na DII
Ulcerative colitis is characterized by mucosal inflammation of the colon.
The first-line agent, 5-aminosalicylic acid or 5-ASA, inhibits leukotriene and ...
Medicamentos para tratamento da doença de Crohn na DII usando agentes imunomoduladores
Crohn's disease is an inflammatory bowel disorder characterized by discontinuous chronic inflammation of the GI tract.
Treatment strategies encompass ...
Medicamentos para o tratamento da doença de Crohn na DII usando agentes biológicos: Anti-TNF
Tumor necrosis factor, or TNF, a proinflammatory cytokine, exists in soluble or membrane-bound form.
TNF-receptor interaction triggers NF-κB, T-cell ...
Medicamentos para tratamento da doença de Crohn na DII usando glicocorticóides
Glucocorticoids, like prednisone, are potent anti-inflammatory agents that induce effective remission in Crohn's patients.
These bind and activate ...
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