Chapter 23
Drugs for Chronic Bowel Disorders
Disturbi cronici intestinali: introduzione
Chronic bowel disorders are long-term medical conditions affecting the digestive tract, including disorders such as irritable bowel syndrome or IBS and ...
Farmaci per il trattamento della sindrome dell'intestino irritabile con diarrea predominante
Diarrhea-predominant irritable bowel syndrome or IBS-D, is characterized by chronic abdominal pain and diarrhea.
Effective IBS-D management involves ...
Farmaci per il trattamento della sindrome dell'intestino irritabile con stitichezza predominante
Irritable bowel syndrome with constipation or IBS-C, is a recurring digestive disorder characterized by abdominal pain and infrequent bowel movements.
...
Farmaci per il trattamento della colite ulcerosa nelle IBD
Ulcerative colitis is characterized by mucosal inflammation of the colon.
The first-line agent, 5-aminosalicylic acid or 5-ASA, inhibits leukotriene and ...
Farmaci per il trattamento del morbo di Crohn nelle IBD mediante agenti immunomodulatori
Crohn's disease is an inflammatory bowel disorder characterized by discontinuous chronic inflammation of the GI tract.
Treatment strategies encompass ...
Farmaci per il trattamento del morbo di Crohn nelle IBD mediante agenti biologici: anti-TNF
Tumor necrosis factor, or TNF, a proinflammatory cytokine, exists in soluble or membrane-bound form.
TNF-receptor interaction triggers NF-κB, T-cell ...
Farmaci per il trattamento del morbo di Crohn nelle IBD con glucocorticoidi
Glucocorticoids, like prednisone, are potent anti-inflammatory agents that induce effective remission in Crohn's patients.
These bind and activate ...
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