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JoVE Journal

Medicine

This content is Open Access.

Coronary Artery Ligation and Intramyocardial Injection in a Murine Model of Infarction

51.4K Views

07:41 min

June 7th, 2011

June 7th, 2011

51,454 Views

0:05

Title

2:22

Surgical Procedure

5:58

Representative Results

7:12

Conclusion

Numerous genetic manipulations and/or intramyocardial injections of genes, proteins, cells, and/or biomaterials are superimposed upon the dimension of time in studies of acute ischemia/ reperfusion injury and chronic remodeling in mice. This video illustrates the microsurgical procedures for ischemia/reperfusion, permanent coronary artery ligation, and intramyocardial injection studies.

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