Transfection Efficiency of mBG/ GFP-pDNA Polyplexes
5:10
Results: Analysis of the Targeted Plasma DNA Delivery
7:11
Conclusion
Transkript
Cationic polymer drug carriers have the advantages of good stability, low immunogenicity, and facile preparation and modification. Here, we offer a rapid and simple method for its synthesis. Reversible addition-fragmentation chain transfer polymer
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This work presents the preparation of methionine functionalized biocompatible block copolymers (mBG) via the reversible addition-fragmentation chain transfer (RAFT) method. The plasmid DNA complexing ability of the obtained mBG and their transfection efficiency were also investigated. The RAFT method is very beneficial for polymerizing monomers containing special functional groups.