Results: Generation of Mammary Epithelial and Endothelial Cell Spheroids
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Conclusion
Transkript
The breast cancer cell spheroids described herein will allow researchers to investigate molecular mechanisms of cancer cell endothelial cell interactions that are involved in proliferation and metastasis of cancer cells. The main advantage of this
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Crosstalk between mammary epithelial cells and endothelial cells importantly contributes to breast cancer progression, tumor growth, and metastasis. In this study, spheroids have been made from breast cancer cells together with vascular and/or lymphatic endothelial cells and demonstrate their applicability as an in vitro system for breast cancer research.