JoVE Logo
Faculty Resource Center

Sign In

Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria

DOI :

10.3791/51174-v

February 23rd, 2014

February 23rd, 2014

14,809 Views

1Department Genetics of Microorganisms, Interfaculty Institute for Genetics and Functional Genomics, University of Greifswald

Streptococcus pneumoniae is the leading pathogen causing severe community-acquired pneumonia and responsible for over 2 million deaths worldwide. The impact of bacterial factors implicated in fitness or virulence can be monitored in real-time in an acute mouse pneumonia or bacteremia model using bioluminescent bacteria.

Tags

Pneumococcal Virulence Factors

-- Views

Related Videos

article

Using Bioluminescent Imaging to Investigate Synergism Between Streptococcus pneumoniae and Influenza A Virus in Infant Mice

article

Real-time Live Imaging of T-cell Signaling Complex Formation

article

Investigating the Effects of Probiotics on Pneumococcal Colonization Using an In Vitro Adherence Assay

article

Capsular Serotyping of Streptococcus pneumoniae Using the Quellung Reaction

article

An Ex vivo Model of an Oligodendrocyte-directed T-Cell Attack in Acute Brain Slices

article

Applying an Inducible Expression System to Study Interference of Bacterial Virulence Factors with Intracellular Signaling

article

Visualizing the Effects of Sputum on Biofilm Development Using a Chambered Coverglass Model

article

Evaluating Virulence and Pathogenesis of Aeromonas Infection in a Caenorhabditis elegans Model

article

Imaging of In Situ Interferon Gamma Production in the Mouse Spleen following Listeria monocytogenes Infection

article

Generation of In-Frame Gene Deletion Mutants in Pseudomonas aeruginosa and Testing for Virulence Attenuation in a Simple Mouse Model of Infection

JoVE Logo

Privacy

Terms of Use

Policies

Research

Education

ABOUT JoVE

Copyright © 2024 MyJoVE Corporation. All rights reserved