June 23rd, 2014
•The rodent retina has long been recognized as an accessible window to the brain. In this technical paper we provide a protocol that employs the mouse model of oxygen-induced retinopathy to study the mechanisms that lead to failure of vascular regeneration within the central nervous system after ischemic injury. The described system can also be harnessed to explore strategies to promote regrowth of functional blood vessels within the retina and CNS.
Tags
Related Videos
Quantifying the Activity of cis-Regulatory Elements in the Mouse Retina by Explant Electroporation
In vivo Electroporation of Developing Mouse Retina
Fast Micro-iontophoresis of Glutamate and GABA: A Useful Tool to Investigate Synaptic Integration
The Corneal Micropocket Assay: A Model of Angiogenesis in the Mouse Eye
Imaging Ca2+ Dynamics in Cone Photoreceptor Axon Terminals of the Mouse Retina
Using the Electroretinogram to Assess Function in the Rodent Retina and the Protective Effects of Remote Limb Ischemic Preconditioning
Mouse Microsurgery Infusion Technique for Targeted Substance Delivery into the CNS via the Internal Carotid Artery
Investigating Mammalian Axon Regeneration: In Vivo Electroporation of Adult Mouse Dorsal Root Ganglion
The Power of Interstimulus Interval for the Assessment of Temporal Processing in Rodents
Transpupillary Two-Photon In Vivo Imaging of the Mouse Retina
ABOUT JoVE
Copyright © 2024 MyJoVE Corporation. All rights reserved