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Oxygen-Induced Retinopathy Model for Ischemic Retinal Diseases in Rodents

DOI :

10.3791/61482-v

September 16th, 2020

September 16th, 2020

7,521 Views

1Faculty of Medicine and Health Technology, Tampere University & Tampere University Hospital, 2Experimentica Ltd, 3Eye Centre, Tampere University Hospital

Oxygen-induced retinopathy (OIR) can be used to model ischemic retinal diseases such as retinopathy of prematurity and proliferative diabetic retinopathy and to serve as a model for proof-of-concept studies in evaluating antiangiogenic drugs for neovascular diseases. OIR induces robust and reproducible neovascularization in the retina that can be quantified.

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Oxygen induced Retinopathy Model

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