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Transplantation of Tail Skin to Study Allogeneic CD4 T Cell Responses in Mice

DOI :

10.3791/51724-v

July 25th, 2014

July 25th, 2014

12,079 Views

1Department of Biomedicine, Immunoregulation, University of Basel and University Hospital Basel

Tail-skin transplantation is a powerful model for studying T cell-dependent rejection and tolerance induction during allogeneic immune responses in mice. The advantages of this protocol are minor invasive surgery, and ease of monitoring with no need to sacrifice the recipient mouse.

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Tail skin Transplantation

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