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Whole-mount Imaging of Mouse Embryo Sensory Axon Projections

DOI :

10.3791/52212-v

December 9th, 2014

December 9th, 2014

9,911 Views

1Brain and Mind Research Institute, Burke Medical Research Institute, Weill Medical College of Cornell University

We present here an optimized protocol to genotype, stain and prepare fetal mice for the imaging of peripheral nociceptor axon projections in the whole animal, as an effective method to assess sensory axon growth phenotypes in developing genetically engineered mice.

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Whole mount Imaging

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