JoVE Logo
Faculty Resource Center

Sign In

Organotypic Hippocampal Slice Cultures As a Model to Study Neuroprotection and Invasiveness of Tumor Cells

DOI :

10.3791/55359-v

August 27th, 2017

August 27th, 2017

12,454 Views

1Department of Anatomy and Cell Biology, Martin Luther University Halle-Wittenberg, 2Department of Anatomy, University of Otago

Organotypic hippocampal slice cultures (OHSC) represent an in vitro model that simulates the in vivo situation very well. Here we describe a vibratome-based improved slicing protocol to obtain high quality slices for use in assessing the neuroprotective potential of novel substances or the biological behavior of tumor cells.

Tags

Keywords Organotypic Hippocampal Slice Cultures

-- Views

Related Videos

article

The Organotypic Hippocampal Slice Culture Model for Examining Neuronal Injury

article

Organotypic Hippocampal Slice Cultures

article

Organotypic Cerebellar Cultures: Apoptotic Challenges and Detection

article

Organotypic Slice Cultures of Embryonic Ventral Midbrain: A System to Study Dopaminergic Neuronal Development in vitro

article

The Analysis of Purkinje Cell Dendritic Morphology in Organotypic Slice Cultures

article

Post-embedding Immunogold Labeling of Synaptic Proteins in Hippocampal Slice Cultures

article

Organotypic Slice Cultures to Study Oligodendrocyte Dynamics and Myelination

article

The Analysis of Neurovascular Remodeling in Entorhino-hippocampal Organotypic Slice Cultures

article

Preparation and Immunostaining of Myelinating Organotypic Cerebellar Slice Cultures

article

Purkinje Cell Survival in Organotypic Cerebellar Slice Cultures

JoVE Logo

Privacy

Terms of Use

Policies

Research

Education

ABOUT JoVE

Copyright © 2024 MyJoVE Corporation. All rights reserved