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Live-cell Imaging of Platelet Degranulation and Secretion Under Flow

DOI :

10.3791/55658-v

July 10th, 2017

July 10th, 2017

11,307 Views

1Department of Clinical Chemistry and Haematology, University Medical Center Utrecht, 2Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences, Utrecht University

This work describes a fluorescence microscopy-based method for the study of platelet adhesion, spreading, and secretion under flow. This versatile platform enables the investigation of platelet function for mechanistic research on thrombosis and hemostasis.

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Keywords Live cell Imaging

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