Results: Transcriptional Upregulation of Acidic responsive Genes in Response to Lactic Acidosis and HCl-mediated Acidosis
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Conclusion
Transcript
The overall goal of this simple in vitro culture method is to elucidate underlying mechanisms of tumor malignancy under an acidic tumor microenvironment. This method can help answer key questions in the tumor biology field, such as the underlying
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The acidic tumor microenvironment plays critical roles in tumor progression. To assess the effects of acidic extracellular pH on cancer cells in vitro, we established simple acidic culture systems.