The overall goal of this porcine closed chest myocardial infarction model is to investigate myocardial ischemia reperfusion injury. This method can help to answer key questions in cardiovascular research such as investigating the pathophysiology o
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Here we demonstrate a protocol to standardize sampling procedures of an established porcine model of acute myocardial infarction in order to increase its translational value in the understanding of the pathophysiology of myocardial ischemia/reperfusion injury and to test novel drug candidates.