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Using Mouse Oocytes to Assess Human Gene Function During Meiosis I

DOI :

10.3791/57442-v

April 10th, 2018

April 10th, 2018

8,565 Views

1IVI-RMA New Jersey, 2Jefferson College of Biomedical Sciences, Thomas Jefferson University, 3Department of Genetics, Rutgers, The State University of New Jersey

As the genetic variants associated with human disease begin to become uncovered, it is becoming increasingly important to develop systems with which to rapidly evaluate the biological significance of those identified variants. This protocol describes methods for evaluating human gene function during female meiosis I using mouse oocytes.

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