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Effects of Blast-induced Neurotrauma on Pressurized Rodent Middle Cerebral Arteries

DOI :

10.3791/58792-v

8:21 min

April 1st, 2019

April 1st, 2019

6,779 Views

1Charles R. Allen Research Laboratories, Department of Anesthesiology, University of Texas Medical Branch, 2The Moody Project for Translational Traumatic Brain Injury Research, University of Texas Medical Branch

Here, we present a protocol to describe methods for ex vivo vascular reactivity determination following a primary blast traumatic brain injury (bTBI) using isolated, pressurized, rodent middle cerebral arterial (MCA) segments. bTBI induction is accomplished using a shock tube, also known as an Advanced Blast Simulator (ABS) device.

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Blast induced Neurotrauma

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