JoVE Logo
Faculty Resource Center

Sign In

Design of a Biocompatible Drug-Eluting Tracheal Stent in Mice with Laryngotracheal Stenosis

DOI :

10.3791/60483-v

January 21st, 2020

January 21st, 2020

6,517 Views

1Department of General Surgery, University of California, San Francisco, 2Department of Otolaryngology Head and Neck Surgery, Johns Hopkins School of Medicine

Laryngotracheal stenosis results from pathologic scar deposition that critically narrows the tracheal airway and lacks effective medical therapies. Using a PLLA-PCL (70% poly-L-lactide and 30% polycaprolactone) stent as a local drug delivery system, potential therapies aimed at decreasing scar proliferation in the trachea can be studied.

Tags

Keywords Biocompatible

-- Views

Related Videos

article

Monitoring the Wall Mechanics During Stent Deployment in a Vessel

article

Design of a Biaxial Mechanical Loading Bioreactor for Tissue Engineering

article

Experimental Investigation of Secondary Flow Structures Downstream of a Model Type IV Stent Failure in a 180° Curved Artery Test Section

article

Ferromagnetic Bare Metal Stent for Endothelial Cell Capture and Retention

article

Automated Robotic Liquid Handling Assembly of Modular DNA Devices

article

Synthesis of Biocompatible Liquid Crystal Elastomer Foams as Cell Scaffolds for 3D Spatial Cell Cultures

article

Anatomically Realistic Neonatal Heart Model for Use in Neonatal Patient Simulators

article

Repressing Gene Transcription by Redirecting Cellular Machinery with Chemical Epigenetic Modifiers

article

Design and Synthesis of a Reconfigurable DNA Accordion Rack

article

Seeding and Implantation of a Biosynthetic Tissue-engineered Tracheal Graft in a Mouse Model

JoVE Logo

Privacy

Terms of Use

Policies

Research

Education

ABOUT JoVE

Copyright © 2024 MyJoVE Corporation. All rights reserved