Results: Representative Cardiac Chamber Remodeling and MR Severity
7:03
Conclusion
Transcript
Mitral regurgitation is a common valve disease that leads to heart failure. This rat MR model can help to further our understanding of the underlying mechanisms of heart failure. This model can be used to induce MR in a beating heart mimicking the
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A rodent model of left heart volume overload from mitral regurgitation is reported. Mitral regurgitation of controlled severity is induced by advancing a needle of defined dimensions into the anterior leaflet of the mitral valve, in a beating heart, with ultrasound guidance.