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In Vitro 3D Cell-Cultured Arterial Models for Studying Vascular Drug Targeting Under Flow

DOI :

10.3791/62279-v

March 14th, 2021

March 14th, 2021

2,935 Views

1Department of Biomedical Engineering, Technion - IIT

Here, we present a new protocol to study and map the targeted deposition of drug carriers to endothelial cells in fabricated, real-sized, three-dimensional human artery models under physiological flow. The presented method may serve as a new platform for targeting drug carriers within the vascular system.

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