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Use of Trowell-Type Organ Culture to Study Regulation of Dental Stem Cells

DOI :

10.3791/62462-v

July 8th, 2021

July 8th, 2021

1,441 Views

1Research Program in Developmental Biology, Institute of Biotechnology, University of Helsinki, 2Department of Oral and Maxillofacial diseases, Faculty of Medicine, University of Helsinki

The Trowell-type organ culture method has been used to unravel complex signaling networks that govern tooth development and, more recently, for studying regulation involved in stem cells of the continuously growing mouse incisor. Fluorescent-reporter animal models and live-imaging methods facilitate in-depth analyses of dental stem cells and their specific niche microenvironment.

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