JoVE Logo
Faculty Resource Center

Sign In

Evaluation of Motor Impairment in C. elegans Models of Amyotrophic Lateral Sclerosis

DOI :

10.3791/62699-v

8:27 min

September 2nd, 2021

September 2nd, 2021

3,150 Views

1Geriatrics Research Education and Clinical Center, Veterans Affairs Puget Sound Health Care System, 2Division of Gerontology and Geriatric Medicine, Department of Medicine, University of Washington

This protocol describes two sensitive assays for discriminating among mild, moderate, and severe motor impairment in C. elegans models of amyotrophic lateral sclerosis, with general utility for C. elegans strains, with altered motility.

Tags

Motor Impairment

-- Views

Related Videos

article

C. elegans Positive Butanone Learning, Short-term, and Long-term Associative Memory Assays

article

Automated Quantification of Synaptic Fluorescence in C. elegans

article

C. elegans Tracking and Behavioral Measurement

article

Extracellularly Identifying Motor Neurons for a Muscle Motor Pool in Aplysia californica

article

In vivo Neuronal Calcium Imaging in C. elegans

article

Motor Nerve Transection and Time-lapse Imaging of Glial Cell Behaviors in Live Zebrafish

article

Dissection and Lateral Mounting of Zebrafish Embryos: Analysis of Spinal Cord Development

article

Methods for Studying the Mechanisms of Action of Antipsychotic Drugs in Caenorhabditis elegans

article

Using Enzyme-based Biosensors to Measure Tonic and Phasic Glutamate in Alzheimer's Mouse Models

article

Author Spotlight: Exploring the Potential of Massage Therapy in Cerebral Palsy Using Animal Models

JoVE Logo

Privacy

Terms of Use

Policies

Research

Education

ABOUT JoVE

Copyright © 2024 MyJoVE Corporation. All rights reserved