Results: Select Genotyping Results Showing a Triploid Dispermic Genotype
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Conclusion
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The primary advantage of our genotyping protocol is that it minimizes contamination with maternal DNA, which is the main challenge when genotyping formalin-fixed, paraffin-embedded molar tissues. Flow cytometry is a fast and inexpensive method tha
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Hydatidiform moles are abnormal human pregnancies with heterogeneous aetiologies that can be classified according to their morphological features and parental contribution to the molar genomes. Here, protocols of multiplex microsatellite DNA genotyping and flow cytometry of formalin-fixed paraffin-embedded molar tissues are described in detail, together with results’ interpretation and integration.