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A Mouse Model of Subchronic and Mild Social Defeat Stress for Understanding Stress-induced Behavioral and Physiological Deficits

DOI :

10.3791/52973-v

November 24th, 2015

November 24th, 2015

18,763 Views

1College of Agriculture, Ibaraki University, 2Cooperation between Agriculture and Medical Science, Ibaraki University, 3United Graduate School of Agricultural Science, Tokyo University of Agriculture and Technology

Here, methods for developing a mouse model of subchronic and mild social defeat stress are described and used to investigate the pathogenic features of depression including hyperphagia- and polydipsia-like symptoms following increased body weight.

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